Determining Factors for Recurrent Pregnancy Loss – Dr Jeyarani Kamaraj
Experiencing pregnancy failure is a prevalent obstetric complication, with a 15% to 20% likelihood of miscarriage. Repeated pregnancy failure, defined as two or more consecutive miscarriages, typically occurs in the first or early second trimester, affecting about 5% of couples attempting to conceive. A significant number of miscarriages may occur before the woman is even aware of her pregnancy. Unlike in the past, where the reasons for recurrent miscarriages often remained unknown, contemporary medical advancements enable more women to identify the underlying causes of their repeated pregnancy loss (RPL).
The risk of recurrent pregnancy failure increases with age, particularly for women aged 40 or older who have a history of repeated miscarriages. In comparison to younger women, older individuals in this category face a significantly higher risk of experiencing further pregnancy complications. Dr. Jeyarani Kamaraj, a top pregnancy doctor in Chennai, is known for her expertise in addressing pregnancy-related challenges, including repeated pregnancy loss. The Aakash IVF Centre, under her guidance, has become a Best IVF hospital for comprehensive and advanced reproductive care. Book your appointment today.
Reasons
Recurrent pregnancy loss can be attributed to various factors, each playing a distinct role in the complexities of reproductive health.
Polycystic Ovarian Syndrome (PCOS):
Prevalent in India, PCOS disrupts ovulation and menstruation due to excessive testosterone production and insulin resistance. Medications and regular monitoring become essential in managing PCOS-related fertility challenges.
Endocrine Problems:
Uncontrolled diabetes, severe thyroid issues, or luteal phase defects have been associated with pregnancy loss. Addressing these concerns before attempting conception is crucial for the embryo’s chances of survival.
Environmental Factors:
Cigarette smoking affects trophoblastic function and increases the risk of recurrent pregnancy loss. Obesity, independent of other factors, is linked to a higher risk of miscarriages in naturally conceiving women. Lifestyle habits like alcohol consumption, cocaine use, and excessive caffeine intake are additional factors associated with an elevated risk of spontaneous miscarriages. Recognizing and addressing these diverse factors is essential in managing recurrent pregnancy loss.
Genetic Abnormalities:
Over 50% of early pregnancy losses are linked to chromosomal issues. Defective chromosomes inherited from either parent can disrupt the proper alignment, leading to deformities in the developing embryo and spontaneous abortion.
Cervical Insufficiency:
Characterized by painless cervical opening resulting in second-trimester delivery, cervical insufficiency can be addressed through cerclage, a procedure to stitch the cervix closed, aiming to prevent premature delivery.
Immunological Disorders:
The body’s perception of sperm and embryos as foreign substances can lead to pregnancy failure. Despite the body’s signaling attempts, mismatches can occur, complicating the process.
Treatment
Research indicates that implementing certain health behavior modifications can enhance the likelihood of a successful subsequent pregnancy after previous miscarriages. For overweight women, weight loss is recommended, while women planning pregnancy are advised to quit smoking and limit alcohol intake. For women experiencing recurrent miscarriages, healthcare professionals tailor investigations based on age, pregnancy history, family history, and prior treatments to identify potential underlying causes. These investigations may encompass thyroid hormone level assessments, blood tests for antiphospholipid antibodies (APLA), ultrasounds to detect uterine abnormalities, genetic testing of parents, and, in some cases, surgery. The treatment approach varies based on the identified causes.
If a chromosomal problem is identified, genetic counseling may be recommended. While many couples with chromosomal rearrangements eventually conceive naturally, fertility treatments like in vitro fertilization (IVF) might be suggested. IVF involves combining eggs and sperm in a laboratory outside the body. Preimplantation genetic screening can be conducted on the embryos before they are implanted in the uterus, allowing the selection of embryos without genetic abnormalities, thereby increasing the chances of a healthy pregnancy.
Initiate your path to a successful pregnancy by booking an appointment with Dr. Jeyarani at the top IVF hospital in Vadapalani, Chennai. Under her expertise, the dedicated fertility team will meticulously conduct investigations, examining genetic factors, hormonal levels, and potential uterine abnormalities.
Do not allow recurrent pregnancy loss to obstruct your aspirations of parenthood. Secure your consultation with the best gynecology Dr. Jeyarani today, marking the initial stride toward a promising and healthful pregnancy journey.
– Aakash Fertility Centre & Hospital
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