Frozen Embryo Transfer
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Frozen Embryo Transfer
Frozen/thawed embryo transfer (FET) is a treatment that involves implanting embryos that were retrieved from the patient during a previous IVF cycle and held safely in a frozen state.
About Frozen Embryo Transfer
Advantages of Frozen Embryo Transfer
Frozen Embryo Transfer Treatment Procedures
The duration of FET treatments vary by patient; in general, most patients fall into the three- to four-week range. The number of embryos transferred depends on several factors: patient age, embryo quality, and the number of embryos available after the thawing process. Again, speaking in general terms, our fertility experts prefer to thaw one more embryo than was transferred in the fresh cycle.Embryos are thawed individually until there are enough available to complete the transfer process as described above. For example, if a patient needs three embryos transferred, initially three will be thawed, and depending on the survival rate, more will be thawed until three viable embryos are obtained. Embryos will be allowed to grow out one or two days after thaw.
Embryo Cryopreservation
Embryos are grown for several days before they are cryopreserved for later use, however may be frozen at any point after fertilization. Indeed, there is general consensus that cryopreservation (freezing) is possible at any stage of embryo development. However while embryos frozen immediately after fertilization, demonstrate capacity to survive the thawing process, the embryos that prove most successful for achieving implantation are allowed to develop in the lab for a day or two prior to the cryopreservation process.
To whom Surrogacy is Advised?
1. IVF Surrogacy
Primarily, IVF surrogacy is indicated in women whose ovaries are producing eggs but they do not have a uterus. For e.g., in the following cases:
Congenital absence of uterus (Mullerian agenesis) Surgical removal of the uterus (hysterectomy) due to cancer, severe hemorrhage in Caesarian section or a ruptured uterus.
A woman whose uterus is malformed (unicornuate uterus, T shaped uterus, bicornuate uterus with rudimentary horn) or damaged uterus (T.B of the endometrium, severe Asherman’s Syndrome) or at high risk of rupture, (previous uterine surgeries for rupture uterus or fibroid uterus) and is unable to carry pregnancy to term can also be recommended IVF surrogacy
Women who have repeated miscarriages or have repeated failed IVF cycles may be advised IVF surrogacy in view of unexplained factors which could be responsible for failed implantation and early pregnancy wastage.
Women who suffer from medical problems like diabetes, cardio-vascular disorders, or kidney diseases like chronic nephritis, whose long term prospect for health is good but pregnancy would be life threatening.
Woman with Rh incompatibility.
2. Traditional Surrogacy
Women who have no functioning ovaries due to premature ovarian failure. Here egg donation also can be an option. A woman who is at a risk of passing a genetic disease to her offspring may also opt for traditional surrogacy. What are the advantages of surrogacy? This may be the only chance for some couples to have a child, which is biologically completely their own (IVF surrogacy) or partly their own (gestational surrogacy) The genetic mother can bond with the baby better than in situations like adoption.